Norditropin SimpleXx (1x30IU)

Simplexx Norditropin (1x30iu)

where to buy recombinant growth hormone is identical in composition and effects of human pituitary growth hormone. It is a polypeptide comprising 191 amino acids. Biological activity of approximately 3 IU / mg. Stimulates skeletal growth and increase body weight; It stimulates the transport of amino acids in the cell, accelerating the synthesis of intracellular proteins and showing the anabolic effects thus. Causes a delay in the body of nitrogen, mineral salts (calcium, phosphorus and sodium) and liquid. Increases in blood glucose levels.
pharmacokinetics
After n / k administration systemic absorption is 80%. plasma Cmax reaches after 3-6 hours and is 13-35 ng / ml. It is metabolized in the liver.
T1 / 2 -. 2-3 hours drift through the gut.
Indications of use:
Deficiency in growth hormone in the body (pituitary dwarfism, hypophyseal dwarfism); chronic renal failure in children, accompanied by stunting; Turner - Shereshevscky syndrome.
Contraindications:
Malignant neoplasms, pregnancy, lactation, hypersensitivity to somatropin.
Growth hormone dosage:
Adjust individually. Typically injected sc / k from 0.07 to 0.1 IU / kg once daily, and in some cases - 0.14-0.2 IU / kg per day.
Growth hormone side effects:
Endocrine system: hyperglycemia, increased symptoms of hypothyroidism.
Allergic reactions: rash, itching, increased titers of antibodies to somatropin.
Other: headache, edema.
Local reactions: pain, redness at injection site.
Application of pregnancy and lactation:
Contraindicated during pregnancy and lactation.
Interaction with other medicinal products:
While the use of corticosteroid efficacy somatropin decreases.
instructions and special precautions:
It should not be used in patients with bone growth that culminated in the process.

Use with caution in patients with diabetes (requires a blood sugar monitor and if it is necessary to increase the dose of insulin). Lack of thyroid function can reduce the effectiveness of growth hormone. In the case of states of hypothyroidism thyroid hormones must be administered.
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